Tobacco Road

Charley Grapewin

Jeeter Lester

Marjorie Rambeau

Sister Bessie Rice

Gene Tierney

Ellie May Lester

William Tracy

Dude Lester

Elizabeth Patterson

Ada Lester

Dana Andrews

Capt. Tim Harmon

Slim Summerville

Henry Peabody

Ward Bond

Lov Bensey

Grant Mitchell

George Payne

Zeffie Tilbury

Grandma Lester

Russell Simpson

Chief of Police

Spencer Charters

County Clerk

Irving Bacon

Bank Teller

Harry Tyler

Car Salesman

Charles Halton

Mayor

George Chandler

Hotel Desk Clark

Dorothy Adams

Susie Mae (uncredited)

Mae Marsh

County Clerk's Assistant (uncredited)

Jack Pennick

Policeman

Erville Alderson

Luke Cosgrave

Francis Ford

David Hughes

John 'Skins' Miller

Robert Shaw